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Glycolic Acid

Glycolic acid peel is the most common alpha-hydroxy acid peel, also known as fruit peel. It is simple, inexpensive, and has no downtime. This review talks about various studies of glycolic acid peels for various indications, such as acne, acne scars, melasma, postinflammatory hyperpigmentation, photoaging, and seborrhea.

Glycolic Acid has the smallest molecular weight amongst all the alpha-hydroxy acids. It penetrates skin easily, making it a popular peel agent. Glycolic Acid has two carbon atoms: one carbon atom is with a carboxyl group and the other carbon atom is with a hydroxyl group. Glycolic Acid is extremely hydrophilic. Glycolic acid peels are commercially available as free acids, partially neutralized (higher pH), buffered, or esterified solutions. They are available in various concentrations. The higher the concentration and lower the pH, the more intense the peeling will be. In general, gel formulations have a slower penetration time and are easier to control.



Sharad J. Glycolic acid peel therapy - a current review. Clin Cosmet Investig Dermatol. 2013;6:281-288. Published 2013 Nov 11. doi:10.2147/CCID.S34029

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