
Ingredient innovation: Non-Neutralized Glycolic Acid
Clinically Proven: Effectiveness of Daily Glycolic Acid
✔ 94% saw less skin pigmentation (dark spots) after application.
✔ 100% saw improvement in the texture of their skin.
PMID: 9598014 & customer survey from Dermatologist’s Choice
True Transformations


Analyze your Skincare Products
Dermatologist’s Choice
The Active, non-neutralized difference

Our products utilize fully active ingredients including non-neutralized glycolic acid and trichloroacetic acid.
When applying real glycolic acid, the skin will experience the Trustworthy Tingle. This tingling sensation is the indication that the glycolic acid is fully active (non-neutralized) and is working as it should by entering the pores.
Dermatologist’s Choice’s non-neutralized glycolic acid provides the full strength of a medical-grade skincare treatment.
Other Skincare Brands
Non-Active or Slightly Active Ingredients

These products contain very slightly active ingredients (or neutralized active ingredients). For example, retinol, vitamin C, ferulic acid, lactic acid, and salicylic acid.
These products typically add buffer ingredients that compromise the effectiveness and expected results from glycolic acid.
Non-active (neutralized) glycolic acid will not effectively penetrate into the deeper layers of skin or the pores, preventing it from activating the skin’s natural regeneration and exfoliation process.

50 Years Utilizing Fully Active Ingredients
Formulated by Dr. Bottiglione, an award-winning dermatologist for 50 years, we care for your skincare the way your dermatologist would by using potent medical-grade treatments that have outlasted all the trends in skincare for decades. You’ll get refreshed, rejuvenated skin and feel healthier and more confident.
Learn more about our flagship ingredient, non-neutralized, glycolic acid